A review of the traditional uses, phytochemical compounds, and pharmacological activities of Vallesia glabra (Cav.) Link (Apocynaceae)

Authors

Abstract

Background: Vallesia glabra (Cav.) Link (Apocynaceae) is traditionally used in dermatological infections and as a desinflammatory. This review aims to collect information on its traditional uses, phytochemical compounds, and pharmacological activities.

Methods: The scientific literature was searched in the databases Scopus, Web of Science, Alicia Repository, ScienceDirect and PubMed Central; 38 documents were selected (26 original articles, 2 review articles, 4 books and 2 theses) from 1939 to 2022.

Results: V. glabra is traditionally used for pain relief, in infections and inflammations, and as an antifungal. Seventeen indole alkaloids of V. glabra have been identified, several of these alkaloids present important pharmacological activities as antimalarial and bactericidal agents demonstrated in in vitro assays.

Conclusions: The traditional use of V. glabra in infections has been pharmacologically demonstrated in in vitro assays, being the terpenoid indole alkaloids, which confer the activity.

Keywords: Traditional uses, phytochemical compounds, pharmacological activities, Vallesia glabra.

Author Biographies

José G. Gavidia-Valencia, Universidad Nacional de Trujillo

Departamento de Bioquímica, Facultad de Farmacia y Bioquímica, Universidad Nacional de Trujillo

Alejandrina María Llaure-Mora, Universidad Nacional de Trujillo

Grupo de Control de Calidad de Plantas Medicinales, Facultad de Farmacia y Bioquímica, Universidad Nacional de Trujillo

Edmundo Arturo Venegas-Casanova, Universidad Nacional de Trujillo

Departamento de Farmacotecnia, Facultad de Farmacia y Bioquímica, Universidad Nacional de Trujillo

Luz Angélica Suárez-Rebaza, Universidad Nacional de Trujillo

Departamento de Farmacotecnia, Facultad de Farmacia y Bioquímica, Universidad Nacional de Trujillo

Felipe Ruben Rubio-López, Universidad Nacional de Trujillo

Departamento de Farmacotecnia, Facultad de Farmacia y Bioquímica, Universidad Nacional de Trujillo

Maritza Rodrigo-Villanueva, Universidad Nacional de Trujillo

Departamento de Farmacotecnia, Facultad de Farmacia y Bioquímica, Universidad Nacional de Trujillo

Mayar Luis Ganoza-Yupanqui, Universidad Nacional de Trujillo

Departamento de Farmacología, Facultad de Farmacia y Bioquímica

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Published

2022-10-24

How to Cite

Gavidia-Valencia, J. G., Llaure-Mora, A. M., Venegas-Casanova, E. A., Suárez-Rebaza, L. A., Rubio-López, F. R., Rodrigo-Villanueva, M. ., Bussmann, R. W., & Ganoza-Yupanqui, M. L. (2022). A review of the traditional uses, phytochemical compounds, and pharmacological activities of Vallesia glabra (Cav.) Link (Apocynaceae). Ethnobotany Research and Applications, 24, 1–15. Retrieved from https://ethnobotanyjournal.org/index.php/era/article/view/4175

Issue

Vol. 24 (2022)

Section

Reviews

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